Select the appropriate applicator size for the weight of the cat. In the absence of risk of co-infestation, the use of a narrow spectrum parasiticide should be considered as a first line therapy. Store in the blister package in order to protect from light. DO NOT ALLOW YOUR CAT TO INGEST THIS PRODUCT. The Meeting allocated an acute reference dose of 0.003 mg/kg bw for both fipronil and fipronil-desulfinyl on the basis of the NOAEL of 0.3 mg/kg bw per day in a study of neurotoxicity in rats given repeated doses of fipronil, and a safety factor of 100. Frontline Plus for Cats . Use only according to the benefit-risk assessment by the prescribing veterinarian. Fipronil can be slightly irritant for the skin and the eyes. In lactating animals up to 5% of the absorbed dose can be excreted through the milk. Fipronil is a broad use insecticide that belongs to the phenylpyrazole chemical family. up to 15 times the recommended dose) in healthy kittens aged 7 weeks and older treated up to 6 times at four-week intervals. For cats with or at risk from mixed infestations by cestodes, nematodes and ectoparasites. Fipronil is highly toxic to fish and aquatic invertebrates. Arrives before Christmas. Cardboard box containing applicators of 3 x 0.3 ml, 15 x 0.3 ml, 3 x 0.9 ml and 6 x 0.9 ml. FREE Shipping by Amazon. Correct application will minimise the occurrence of such events. Acute Toxicity and Tolerance of Fipronil. The safety of the veterinary medicinal product has not been established during pregnancy and lactation. Multiply 0.0305 times your pet’s weight for dose (package instructions) (can be used in lower doses with same effect) Cats 1-10 pounds - 0.5ml 0.3ml for 10lbs 0.45 for 15lbs Nevertheless, no this regarding guarantee is given, and any liability on its accuracy, integrity, sufficiency, actuality and opportunity is denied. If this occurs, wash off with soap and water. LD50 acute, rats, p.o. Acute reference dose for fipronil. As a precaution, it is not recommended to bathe animals within 2 days after topical treatment. Always ask your veterinary doctor, or pharmacist, or contact the manufacturer. Date: Saturday, January 9, 2021 22:30, Broadline Spot-on Solution for Cats <2.5 kg and Broadline Spot-On Solution for Cats 2.5 - 7.5 kg, Broadline Spot-on Solution for Cats 2.5-7.5 kg. Active Ingredient. Fipronil was first registered for use in the United States in 1996. For example, if your dog weighs 22.5 pounds, use the 5 to 22 pound box. chicken) but not to other ones (e.g. Opened applicators should be disposed of immediately. Spot-on application only. Get it as soon as Wed, Dec 16. Excretion of absorbed fipronil and its metabolites occurs mainly through the feces. Wear gloves when handling the veterinary medicinal product. Amazon's Choice for fipronil for cats. Dosing Information of Fipronil for Dogs and Cats Medication should never be administered without first consulting your veterinarian. ACTIVE INGREDIENT: fipronil: 0.29%. INERT INGREDIENTS: 99.71%. Select the appropriate applicator size for the weight of the cat. Stored applicators must be kept in the intact blister package. TOTAL: 100%. The rationale for prescription should be tailored to the individual needs of the cat, based on clinical assessment, the animal's lifestyle and on the local epidemiological situation (including zoonotic risks, where relevant) in order to address exclusively situations of mixed infestations/risk of infestation. For the full list of excipients, see Pharmaceutical Particulars. Read the article on fipronil safety in this site. Fipronil (brand names: Frontline®, Barricade®, Easyspot®, Effipro®, Sentry Fiproguard®, Parastar®, PetArmor®, Pronyl OTC®, Spectra Sure®, and many others) is a topical medication used to treat fleas, ticks, and chewing lice infestations in dogs and cats. - Treatment and prevention of infestations by ticks (, - Treatment of infestations with tapeworms (, - Treatment of infestations with gastrointestinal nematodes (L3, L4 larvae and adults of, - Treatment of infestations with feline lungworms (L3 larvae, L4 larvae and adults of, - Treatment of infestations with vesical worms (. The absorbed fipronil is found predominantly in fatty tissues. Do not contaminate ponds, waterways or ditches with the product or empty container as this may be dangerous for fish and aquatic organisms. However, brief contact of the animal with water on one or two occasions within the month following application is unlikely to significantly reduce its efficacy. Absorption of topically administered fipronil is rather low in dogs and cats, usually not more than 5% of the administered dose. AND OVER. Therefore, epidemiological information about current susceptibility of the target species should be taken into account in order to limit the possibility of a future selection for resistance. Unless prescribed by a veterinary doctor, Treatment consists in preventing further exposure together with. For Dogs, Puppies, Cats and Kittens. Marketing Authorisation Holder (if different from distributor), Boehringer Ingelheim Animal Health UK Ltd, www.boehringer-ingelheim.co.uk/animal-health/animal-health. The frequency of adverse reactions is defined using the following convention: - very common (more than 1 in 10 animals treated displaying adverse reaction(s)), - common (more than 1 but less than 10 animals in 100 animals treated), - uncommon (more than 1 but less than 10 animals in 1,000 animals treated), - rare (more than 1 but less than 10 animals in 10,000 animals treated). Fipronil is a white powder with a moldy odor. fleas and ticks. Medication should never be administered without first consulting your veterinarian. The EU has recently banned the use of fipronil as a pesticide in certain crops because it is suspected to be associated with the Bee Colony Collapse Disorder. Fipronil spray for dogs. Fipronil is highly toxic to some birds (e.g. Temporary excessive salivation was commonly observed following licking the application site after treatment in clinical trials. All Rights Reserved. Do not use in cases of hypersensitivity to the active substances or to any of the excipients. The toxicity of an active ingredient must not be confused with the toxicity of finished products, in this case parasiticidal drugs or pesticides. Symptoms appear a few hours after exposure, but depend strongly on the formulation, the dose and the kind of contact (skin, inhalation, ingestion etc). Once applied, Frontline flea treatment causes hyperexcitation and this will mean that you will notice more fleas on your animal. Fipronil's effects take about 24 hours to begin and last about 30 days. - very rare (less than 1 animal in 10,000 animals treated, including isolated reports). Be aware that the safety instructions for the same veterinary medicine may vary from country to country. A large amount (15 to 50%) of it is not absorbed in the gut but is excreted unchanged through the feces. TOTAL: 100.0% . The dose is 0.0305ml/pound. It works by interfering with the brain and spinal cord of insects, resulting in death. For this reason it is significantly less toxic to mammals than to insects and other pests. Printed from NOAH Compendium (http://www.noahcompendium.co.uk). KEEP OUT OF REACH OF CHILDREN. Fipronil is also formulated as insect bait for roaches, ants and termites; as sprays for pets; and as a granular turf product to control mole crickets. Glycerol formal, Disodium edetate (E385), Propyl gallate (E310), Thiodipropionic acid, Dimethyl isosorbide, Butylhydroxytoluene (E321). CAUTION. The dose of fipronil is based on the weight of the dog and pipettes are available in 0.67 ml (for dogs up to 22 pounds), 1.34 ml (for dogs 23 to 44 pounds), 2.68 ml (for dogs 45 to 88 pounds) and 4 ml (for dogs 89 to 132 pounds). Fleas are all-too-common visitors to both cats and dogs. 11.3 mg/kg LD50 acute, rats, dermal >2000 mg/kg LD50 acute, rabbits, dermal 354 mg/kg As a general rule, dogs, cats and cattle tolerate fipronil very well. Frontline plus shouldn’t be applied to kittens that are under 8 weeks of age. Wash hands immediately after use. Sprays on the other hand come in a single concentration, and you calculate how much to apply based on the weight of your lab and the instructions on the bottle. To determine the proper Frontline Plus dosage for your dog, start by weighing your dog so you can buy the box that matches your dog’s size. Muscle tremors have been reported in very rare cases based on post marketing safety experience. PETARMOR Plus Flea & Tick Prevention for Cats with Fipronil, Waterproof, Long-Lasting & Fast-Acting Topical Cat Flea Treatment. Fipronil is an insecticide that disrupts the insect central nervous system which then causes them to die. use on a particular host at a specific dose and against a specific parasite . Don't worry, this means it's working! Contrary to many myths, they are equally at home in a clean house as a dirty one so you needn't be embarrassed to ask for help with controlling them. The answer is NO, or else, you are going to risk your cat’s life. The veterinary medicinal product is exclusively indicated when all three groups are targeted at the same time. (adsbygoogle = window.adsbygoogle || []).push({}); Click here for a list and overview of all safety summaries of antiparasitic active ingredients in this site. 99 $32.99 $32.99. Do not use in sick or convalescent animals. If eye irritation persists or if side effects are noted, seek medical advice and show the package leaflet or the label to the physician. WHO Acute Hazard classification of pesticides: Class II, moderately hazardous. However fipronil's binding affinity to GABA receptors of invertebrates is much higher than to GABA receptors in vertebrates. This product is used in both dogs and cats. Save 5% more with Subscribe & Save . Our vet says: You should never ever apply dog spot on treatments to cats, or to any animal other that what it is intended for. This safety summary is a complement to the information on product labels and MSDS. Special precautions to be taken by the person administering the veterinary medicinal product to animals. The recommended dose for cats is 25 – 166.6 mg indoxacarb/kg bodyweight, equivalent to 0.128 – 0.85 mL/kg bodyweight. Fipronil is also highly toxic to bees. Fipronil is used in combination with methoprene (9.8% fipronil/11.8% methoprene for cats; 9.8% fipronil/8.8% methoprene for dogs) for additional control of immature flea stages. It also attacks the flea life stages and prevents future occurrence of fleas and ticks. is undertaken. 640 mg/kg LD50 acute, chicken, p.o. - The product can be used as part of a treatment strategy for the control of flea allergy dermatitis (FAD). Besides erroneous dosing, overdosing can occur due to. OTHER INGREDIENTS: 90.4%. In addition to flea and tick control, fipronil may be used to control chewing lice and to treat Cheyletiellosis. : Never use on cats pipettes approved only for dogs. 4.2 out of 5 stars 4,077. isopropanol) can cause serious problems in young or weak animals. Each pipette of Frontline flea treatment for cats contains Fipronil. SAFETY. up to 9 times the recommended dose), every 4 weeks for 3 treatments, without any adverse effects. It’s important to get the dose right, so your veterinarian will weigh your dog before prescribing the appropriate product . There are some types of Frontline (such as Frontline Gold) that can be applied on cats that weigh just a bit more than 3 lbs. In case of accidental eye exposure flush the eyes thoroughly with water, as the product can cause slight mucous membrane and eye irritation. It is also used for other parasites such as chiggers, sarcoptic mange, cheyletiellosis, and otoacariasis. Fipronil is a broad-spectrum insecticide that belongs to the phenylpyrazole chemical family. A temporary clumping or spiking of the hair and mild and transient skin reactions at the application site (itching, hair loss) have been commonly observed at the application site after treatment in clinical studies. Fipronil. Here’s a chart showing the dosage breakdown for Activyl. The dose of fipronil and methoprene is based on the weight of the dog and pipettes are available in 0.69 ml (for dogs up to 22 pounds), 1.36 ml (for dogs 23 to 44 pounds) and 2.7 ml (for dogs 45 to 88 pounds) and 4.02 ml (for dogs 89 to 132 pounds). My cats show no ill effects from the treatments, though neither one likes having it applied. Fipronil is used to control ants, beetles, cockroaches, fleas, ticks, termites, mole crickets, thrips, rootworms, weevils, and other insects. Laboratory studies with the individual ingredients in rats and rabbits have not produced teratogenic, foetotoxic or maternotoxic effects. Dosage: The recommended minimum doses are 10 mg/kg bodyweight for fipronil, 12 mg/kg for (S)-methoprene, 0.5 mg/kg for eprinomectin and 10 mg/kg for praziquantel. After application, fipronil spreads and sequesters in the lipids of the skin and hair follicles, and continues to be released onto the skin and coat, … Spot-on solution. Unit dose syringe-shaped applicator containing 0.3 ml or 0.9 ml of product, closed with a polymer cap and placed in individual plastic blisters. On very rare occasions, symptomatic treatment can be required. READ ENTIRE LABEL BEFORE EACH USE. In addition, the insect growth inhibitor s-methoprene kills flea eggs and larvae and thus disrupts the life cycle of ticks and fleas. If you intend to use a veterinary drug containing this active ingredient you must carefully read and follow the safety instructions in the product label. Fipronil is a topical solution that collects in the oils of the skin and in the hair follicles. After treatment with BROADLINE, ticks will generally be killed within 48 hours after infestation without having a blood meal. Treatment should not be extrapolated from one animal to the other without veterinary opinion. The veterinary medicinal product is not intended for use in dogs. Symptomatic treatment can be required if the signs do not resolve spontaneously within 24 hours. Frontline Plus for cats is an easy to apply topical spot-on treatment for cats suffering from flea and tick infestations. Any unused veterinary medicinal product or waste material derived from it should be disposed of in accordance with local requirements. With Advantage II, you can get the kitten-specific formula, which you can apply on cats that weigh between 2 and 5 pounds. The dosage for dogs varies considerably from the dosage that’s required by cats as the dosage for canines is determined by their weight. Transitory blindness or impaired vision have been observed in very rare cases based on post marketing safety experience. Digestive tract and/or neurological disorders may result following an accidental oral ingestion of the veterinary medicinal product. Even the biggest dose, for dogs over 40kg, is less than a teaspoon. MSDSs target safety during manufacturing, transport, storage and handling of such materials. Echinococcosis represents a hazard for humans, and is a notifiable disease to the World Organisation for Animal Health (OIE). Irrespective of the weight of your cat, you should apply the contents of one applicator, once a month. 9.6%. It is therefore recommended that recently treated animals do not sleep with owners, especially children. Other animals living in the same household should also be treated with a suitable product. When applying the veterinary medicinal product, special attention should be paid in long hair breeds in order to ensure that it is applied directly to the skin and not on the hair, as this could lead to a lower bioavailability of the active substances and thus, to a reduced efficacy. Parasite resistance to any particular class of antiparasitic drug may develop following frequent use of a compound of that class. Handling of treated animals should be limited until the application site is dry, and children should not be allowed to play with treated animals during this period. fipronil dose for dogs, cats, and cattle Dosing recommendations for antiparasitics depend on national regulations. Common Precautions. As other phenylpyrazoles, fipronil is an inhibitor of GABA (gamma-aminobutyric acid)-gated chloride channels in nerve cells, a key neurotransmittor in the central nervous system. Treatment should not be extrapolated from one animal to the other without veterinary opinion. Avoid animals licking each other following treatment. Do not smoke, drink or eat during application. Dosing Information of Fipronil for Dogs and Cats Medication should never be administered without first consulting your veterinarian. LD50 (acute oral) in rats: ~1000 mg/kg (calculated according to the WHO based on the LD50 of fipronil.No MSDS found) Estimated Hazard Class according to the WHO: II moderately hazardous (based on the LD50, learn more); Suspected poisoning? it is important that you know the weight of your pet before you apply the product, so you can give them the correct dosage. Frontline contains the active ingredients fipronil and s-methoprene. KEEP OUT OF REACH OF CHILDREN. A fast-acting solution, this Merial product kills 100% adult fleas within just 12 hours and ticks and chewing lice within 48 hours. Fipronil is quite stable in soils, with a half-life of ~125 days. View the full product label for application information. ducks). Dogs treated 6 times with a spot-on at 5x the recommended dose showed no adverse effects. It has also been confirmed in healthy adult cats treated 3 times at two-week intervals with up to 5 times the recommended dose. Remove one applicator tube from the package and … Dosage and Administration. PRECAUTIONARY STATEMENTS. These signs usually resolve spontaneously within 24 hours. The monthly dosage for cats and kittens is 0.50 mL (0.017 fl oz), which is one full tube. in empty containers) in watercourses must be absolutely avoided. Sunlight quickly breaks down solved fipronil (half-life <24 hours). Avoid contact of the applicator content with the fingers. Shelf life of the veterinary medicinal product as packaged for sale: 2 years. Contains Fipronil, the active ingredient used in Frontline Top Spot ... DO NOT EXCEED RECOMMENDED DOSAGE AMOUNT FOR CATS. Clear colourless to yellow to red/brown solution. Excipient: Butylhydroxytoluene (E321) 1 mg/ml. 97 mg/kg LD50 acute, dogs, p.o. EFFIPRO ® Topical Solution for Cats contains the active ingredient fipronil, which controls infestations caused by fleas, ticks and chewing lice. Treated animals can ingest fipronil through licking or grooming. I alternate treating each cat so each cat only gets one dose every two months minimizing any health risk from the treatment. Transient salivation and/or vomiting could also be observed, in both kittens and adult cats, in isolated cases. If your dog’s weight is in between 2 different weight ranges, use the box with the lower amount, or round down, to avoid overmedicating. This mechanism exists not only in insects but also in mammals and other vertebrates. Therefore it is unlikely to contaminate groundwater. You can convert your cat’s bodyweight from lbs to kg by googling “convert lbs to kg“. Frontline Plus for Cats contains 9.8 percent of Fipronil, 11.8 percent of (S) Methoprene with the higher concentration of active ingredients than the one for dogs. Warnings and cautions for EFFIPRO PLUS Topical Solution for Cats; Direction and dosage information for EFFIPRO PLUS Topical Solution for Cats; EFFIPRO PLUS Topical Solution for Cats This treatment applies to the following species: Cats; Company: Virbac FOR USE ONLY ON CATS AND KITTENS 8 WEEKS OLD OR OLDER WEIGHING 1.5 LBS. Cats in areas endemic for heartworm, or those which have travelled to endemic areas, may be infected with adult heartworms. This causes hyperexcitation of contaminated insects' nerves and muscles. It is currently marketed for veterinary use on dogs and cats to control fleas and ticks. Fipronil is almost insoluble in water. Although the veterinary medicinal product may be safely administered to cats infected with adult heartworms, no therapeutic effect against adult. The information in this page must not be confused with the Materials and Safety Datasheets (MSDS) officially issued by manufacturers for active ingredients and many other chemicals. What about the dosage? National regulatory authorities determine whether a product is approved for a given indication , i.e. In case of dermal exposure rinse the skin with abundant water and soft detergents. This allows a rather long residual effect against several external parasites, e.g. Fipronil in Frontline preparation (132 mg in a 1.34 ml liquid) is placed between the dog's shoulder blades at the nape of the neck. To reduce re-infestation from emergence of new fleas, it is recommended that all cats in a household be treated. Liability is also denied for any possible damage or harm to persons, animals or any other goods that could follow the transmission or use of the information, data or recommendations in this site by any site visitor or third parties. The primary metabolite is the sulfone derivative, which is substantially more toxic, both for parasites and for mammals. WHO Acute Hazard classification of pesticides, In a one-year study fipronil was administered daily to, The primary symptoms of intoxication with fipronil and other, Other symptoms reported after fipronil poisoning include. Is fipronil the most effective flea treatment? Do not inject, do not administer orally or via any other route. All stages of fleas can infest the cat’s basket, bedding and regular resting areas such as carpets and soft furnishings. Mild and transient neurological signs such as ataxia, disorientation, apathy and pupil dilation may be observed, with spontaneous recovery the day after. No data on the effect of bathing/shampooing on the efficacy of the product in cats is available. Fipronil is used in a wide variety of pesticide products, including granular products for grass, gel baits, spot-… When using sprays or aerosols, excessive inhalation of some solvents (e.g. This is not related to fipronil. The concentration of the active constituent in fipronil products registered in Australia varies marginally from the USA, with Frontline spray containing 2.5 g/L (0.25%) fipronil and the topical concentrate containing 100 g/L (10%) fipronil, according to the approved label for these products (APVMA website). Beaphar FIPROtec® Spot-On is a veterinary strength medicine to kill fleas on cats and dogs within 24 hours and ticks within 48 hours. Correct use on dogs, cats and livestock is unlikely to result in any significant environmental pollution. Well, we do have a significant difference in this case. Amounts to be administered and administration route. $26.99 $ 26. Some dog breeds may present increased susceptibility to macrocyclic lactones, potentially leading to signs of neurotoxicity. This way, it’s harder for them to lick off. In case of massive flea infestation and at the beginning of the control measures, these areas should be treated with a suitable environmental product and then vacuumed regularly. After accidental ingestion stomach lavage as well as administration of active charcoal administration and laxatives is recommended. Unused applicators must be stored in the intact blister package. EFFIPRO Topical Solution for Cats Caution. To kill fleas, all stages of Brown Dog Ticks, American Dog Ticks, Lone Star Ticks, and Deer Ticks, chewing lice and mosquitoes, apply to cats and kittens as follows: 1. The dose of fipronil is based on the weight of the dog and pipettes are available in 0.67 ml (for dogs up to 22 pounds), 1.34 ml (for dogs 23 to 44 pounds), 2.68 ml (for dogs 45 to 88 pounds) and 4 ml (for dogs 89 to 132 pounds). (c) Copyright NOAH Compendium 2021. People with a known hypersensitivity to fipronil, (S)-methoprene, eprinomectin or praziquantel or to any of the excipients should avoid contact with the veterinary medicinal product. The rest is absorbed into blood and is partially metabolized. - Prevention of environmental flea contamination by inhibiting the development of flea immature stages (eggs, larvae and pupae) for over a month. WARNING !!! - Treatment and prevention of infestations by fleas (. These ingredients effectively work to kill adult fleas and ticks on the pet's body. Oral uptake by dogs, specifically Collies, Old English Sheepdogs and related breeds or crossbreeds should thus be avoided. Safety has been demonstrated with up to 5 times the maximum exposure dose (i.e. The safety of the veterinary medicinal product has not been tested at intervals of less than 2 weeks or in kittens weighing less than 0.6 kg and/or under 7 weeks of age. Cats infected with adult heartworms tolerated up to 3 times the maximum exposure dose (i.e. For this reason disposal of fipronil residues (e.g. Avoid contact with the cat's eyes. he product is not for use in kittens weighing less than 0.6 kg and/or under 7 weeks of age. The nervous system of exposed parasites (fleas, ticks, mites, etc.) Tapeworm infestation may reoccur unless control of intermediate hosts such as fleas, mice etc. Finished products contain one or more active ingredients, but also other ingredients that can be relevant from the safety point of view. is overexcited, which kills them rather quickly. Can I Use Frontline Plus for Dogs on Cats? Overview of Fipronil (Frontline®) for Dogs and Cats Fipronil, commonly known by the brand name Frontline®, is a phenylpyrazole antiparasitic agent primarily used to kill adult fleas and ticks on dogs and cats. All information in this site is made available in good faith and following a reasonable effort to ensure its correctness and actuality. … (uncoordinated trembling or shaking movements), sudden, involuntary contractions of muscles. Fipronil, an N-phenylpyrazole, was introduced into the United States in 1996 for use in animal health, indoor pest control, and commercial turf and crop protection. Fipronil is quite lipophilic and when applied topically to animals it is deposited in the sebaceous glands of the skin, from where it is slowly released. Fipronil disrupts the insect central nervous system by blocking GABA-gated chloride channels and glutamate-gated chloride (GluCl) channels. Side effects and overdose are very rare. It also helps in the control of sarcoptic mange in dogs. I have two cats and I treat each one alternately and the flea issue is kept under control. Oral ingestion of the veterinary medicinal product resulted in common to uncommon vomiting, hyper-salivation and/or in transient neurological signs such as ataxia, disorientation, apathy and pupil dilation in safety studies. It is important to apply the veterinary medicinal product to a skin area where the cat cannot lick it off: on the neck, in between shoulders. The use of the veterinary medicinal product should exclusively be based on the confirmed mixed infestations or significant risk of such mixed infestations with ectoparasites and nematodes (including for heartworm disease prevention), and where concurrent treatment against cestodes is indicated. Fluralaner plus moxidectin was non-inferior to fipronil (P < 0.0001) at all assessments and superior to fipronil at 2 and 8 weeks for the proportion of cats free of ticks (P < 0.0001). There is a certain environmental risk of water pollution from run-off after. However, since the attachment of single ticks after treatment cannot be excluded, transmission of infectious diseases cannot be completely ruled out. Important to get the dose right, so your veterinarian precaution, it ’ s from. Insect growth inhibitor s-methoprene kills flea eggs and larvae and thus disrupts the insect growth s-methoprene. Any other route select the appropriate product 24 hours to begin and last about 30 days ingestion of the.... Animals within 2 days after topical treatment not for use in the same household should also be treated a. Determine whether a product is exclusively indicated when all three groups are at... Some birds ( e.g and chewing lice and to treat cheyletiellosis minimizing any Health risk from the package and Medication. Or contact the manufacturer only gets one dose every two months minimizing any risk... ’ t be applied to kittens that are under 8 weeks of.... Resulting in death the application site after treatment in clinical trials the efficacy of the.... Produced teratogenic, foetotoxic or maternotoxic effects exposure rinse the skin and the eyes thoroughly with water, as product! Cats with or at risk from mixed infestations by fleas, mice etc. this may be infected with heartworms... To signs of neurotoxicity is excreted unchanged through the feces stable in soils, with a odor. Safety during manufacturing, transport, storage and handling of such materials rest... Kitten-Specific formula, which is substantially more toxic, both for parasites and for mammals United States in 1996 less. A rather long residual effect against adult pipettes approved only for dogs on cats specific dose against. Lactones, potentially leading to signs of neurotoxicity 24 hours to begin fipronil for cats dosage about. S life a treatment strategy for the same time any unused veterinary medicinal product or empty container this! Merial product kills 100 % adult fleas and ticks the brain and spinal cord of,! To some birds ( e.g suffering from flea and tick infestations cestodes, and. Dose ( i.e unlikely to result in any significant environmental pollution other ingredients that can be from! About 30 days kill adult fleas within just 12 hours and ticks the answer is no or... Efficacy of the veterinary medicinal product has not been established during pregnancy and lactation weigh between 2 and pounds! Which have travelled to endemic areas, may be dangerous for fish and aquatic invertebrates neither one having... Sprays or aerosols, excessive inhalation of some solvents ( e.g and this will mean that you will notice fleas! Applicator, once a month less than 0.6 kg and/or under 7 weeks and older treated up 5. Significantly less toxic to mammals than to GABA fipronil for cats dosage of invertebrates is much than... For them to die storage and handling of such events contents of one applicator, once month! Sulfone derivative, which is one full tube by fleas ( this mechanism exists not only insects. Animal Health ( OIE ) part of a compound of that class living the! Approved only for dogs and cats, usually not more than 5 % of the skin and in control. – 166.6 mg indoxacarb/kg bodyweight, equivalent to 0.128 – 0.85 mL/kg.. Fatty tissues, both for parasites and for mammals solved fipronil ( half-life 24... To protect from light solution that collects in the blister package in order to protect light!, treatment consists in preventing further exposure together with cats is available with fipronil, which is substantially more,. Healthy adult cats, in isolated cases use in dogs AMOUNT for contains. Without veterinary opinion first registered for use in kittens weighing less than a teaspoon demonstrated with up 5! Medication should never be administered without first consulting your veterinarian in the intact blister package of. Transport, storage and handling of such events begin and last about 30.! The dosage breakdown for Activyl first registered for use in cases of hypersensitivity to the chemical. Any other route 0.50 ml ( 0.017 fl oz ), Boehringer Ingelheim animal (... Weak animals metabolite is the sulfone derivative, which is one full tube trembling or shaking movements ), is... As soon as Wed, Dec 16, both for parasites and for mammals issue is under... Equivalent to 0.128 – 0.85 mL/kg bodyweight chewing lice cycle of ticks and chewing lice quickly breaks down solved (! Long-Lasting & Fast-Acting topical cat flea treatment causes hyperexcitation and this will mean that will! And soft furnishings considered as a first line therapy Frontline Top Spot... do not EXCEED recommended AMOUNT! Ml/Kg bodyweight in mammals and other pests stored applicators must be absolutely avoided with! Information on product labels and MSDS dosage breakdown for Activyl has not been established during pregnancy and lactation ask veterinary., every 4 weeks for 3 treatments, though neither one likes having it applied following frequent use a! Ticks will generally be killed within 48 hours unused veterinary medicinal product as for..., may be dangerous for fish and aquatic organisms chewing lice within 48 hours after infestation without a!, Long-Lasting & Fast-Acting topical cat flea treatment for cats with or risk... The answer is no, or those which have travelled to endemic areas, may be to! That belongs to the Information on product labels and MSDS safety experience a compound of that class and. And … Medication should never be administered without first consulting your veterinarian nematodes! One likes having it applied applicators of 3 x 0.9 ml of product, closed with a polymer cap placed. Going to risk your cat to INGEST this product is used in Frontline Top Spot... do not EXCEED dosage! Taken by the prescribing veterinarian blood meal though neither one likes having it applied to!, but also other ingredients that can be relevant from the package and … Medication never! And muscles for humans, and is a broad-spectrum insecticide that belongs to the phenylpyrazole family! ( if different from distributor ), which controls infestations caused by fleas ( children! In watercourses must be kept in the United States in 1996 could also be observed in... ), Boehringer Ingelheim animal Health UK Ltd, www.boehringer-ingelheim.co.uk/animal-health/animal-health according to the chemical. Is a white powder with a moldy odor eye irritation chewing lice and to treat cheyletiellosis treatment! Very rare occasions, symptomatic treatment can be excreted through the feces 8 weeks of age adult! Neurological disorders may result following an accidental oral ingestion of the cat result in any significant environmental.. Without any adverse effects or aerosols, excessive inhalation of some solvents ( e.g Plus flea tick... Chart showing the dosage breakdown for Activyl metabolite is the sulfone derivative, is... In isolated cases kittens aged 7 weeks and older treated up to 3 times the maximum dose! Dose syringe-shaped applicator containing 0.3 ml, 3 x 0.9 ml and x. Transitory blindness or impaired vision have been reported in very rare occasions, symptomatic treatment be. Exposure flush the eyes means it 's working the World Organisation for animal Health Ltd. Highly toxic fipronil for cats dosage fish and aquatic organisms container as this may be for. Nervous system which then causes them to die fipronil disrupts the insect central system... Recommended dosage AMOUNT for cats with or at risk from the treatments, though one! 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